Quantum Computing in Software Design: A Systematic Literature Review

Abstract

Quantum computing represents one of the most transformative technological shifts in computational science since the advent of classical computing architectures. This systematic literature review (SLR) synthesizes 212 peer-reviewed studies published between 2015 and 2024 to map the current landscape of quantum computing research as it intersects with software development practices, tools, frameworks, and methodologies. Following the PRISMA 2020 guidelines, we searched six major academic databases and identified relevant literature through a rigorous multi-stage screening process. Our analysis reveals five dominant research themes: quantum algorithm development and software frameworks, quantum machine learning integration, quantum cryptography and security applications, quantum software testing and verification, and hybrid quantum-classical software architectures. We further document major challenges including hardware decoherence, limited qubit availability, the absence of mature quantum DevOps pipelines, and a critical shortage of quantum-competent software engineers. The review concludes with a structured research agenda identifying six high-priority gaps where future scholarly work is most urgently needed. This paper provides a foundational reference for software engineers, researchers, and technology strategists seeking to understand and navigate the rapidly evolving quantum software ecosystem.