Preliminary Phytochemical and Antimicrobial Screening of the Leave Extracts of Uvaria Chamae

Abstract

Phytochemical screening and antimicrobial activities of aqueous and ethanol leave extract of U. chamae, were studied using paper disc diffusion method against Streptococcus pyogen, Escherichia coli and Salmonella thypi. The results of the antimicrobial studies indicated that the extracts inhibited the growth of one or more tested pathogens. The ethanolic extract showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, alkaloids, glycosides, flavonoids, carbohydrates and terpenes. Anthraquinone and glycoside were not present. Inhibition zone by the extracts ranges from 6.0 mm to 29 mm. The Minimum Inhibitory concentration (MIC) ranges from 100 mg/mL to 6.25 mg/mL. Uvaria chamae leave may be able to produce antimicrobial agents in drug delivery.